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dld1 ecacc  (ATCC)


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    Structured Review

    ATCC dld1 ecacc
    In vitro antitumor activity of undigested and digested red grape anthocyanin extracts in <t>DLD1</t> and Caco2 cells. ( A ) MTT cell viability curves; ( B ) IC₅₀ values and relative potency; ( C ) Representative cell morphology of untreated (CTR) and IC₅₀-treated cells; ( D ) Trypan Blue viability validation in DLD1 cells. Statistical significance was assessed by t-test and Extra Sum-of-Squares F Test
    Dld1 Ecacc, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 3881 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dld1 ecacc/product/ATCC
    Average 99 stars, based on 3881 article reviews
    dld1 ecacc - by Bioz Stars, 2026-06
    99/100 stars

    Images

    1) Product Images from "Gastrointestinal Digestion Enhances the In vitro Antitumor Activity of Red Grape Anthocyanins Against Colorectal Cancer Cells"

    Article Title: Gastrointestinal Digestion Enhances the In vitro Antitumor Activity of Red Grape Anthocyanins Against Colorectal Cancer Cells

    Journal: Plant Foods for Human Nutrition (Dordrecht, Netherlands)

    doi: 10.1007/s11130-026-01498-w

    In vitro antitumor activity of undigested and digested red grape anthocyanin extracts in DLD1 and Caco2 cells. ( A ) MTT cell viability curves; ( B ) IC₅₀ values and relative potency; ( C ) Representative cell morphology of untreated (CTR) and IC₅₀-treated cells; ( D ) Trypan Blue viability validation in DLD1 cells. Statistical significance was assessed by t-test and Extra Sum-of-Squares F Test
    Figure Legend Snippet: In vitro antitumor activity of undigested and digested red grape anthocyanin extracts in DLD1 and Caco2 cells. ( A ) MTT cell viability curves; ( B ) IC₅₀ values and relative potency; ( C ) Representative cell morphology of untreated (CTR) and IC₅₀-treated cells; ( D ) Trypan Blue viability validation in DLD1 cells. Statistical significance was assessed by t-test and Extra Sum-of-Squares F Test

    Techniques Used: In Vitro, Activity Assay, Biomarker Discovery

    Transcriptomic alterations in DLD1 cells treated with IC₅₀ of digested red grape anthocyanins. ( A ) Hierarchical clustering of microarray samples; ( B ) Volcano plot of differentially expressed genes (|FR| ≥ 1.5; adj. p < 0.05); ( C ) Heatmap of top 50 up- and downregulated genes; ( D ) Enriched Hallmark and Reactome gene sets identified by GSEA (FDR < 25%, nominal p < 0.05)
    Figure Legend Snippet: Transcriptomic alterations in DLD1 cells treated with IC₅₀ of digested red grape anthocyanins. ( A ) Hierarchical clustering of microarray samples; ( B ) Volcano plot of differentially expressed genes (|FR| ≥ 1.5; adj. p < 0.05); ( C ) Heatmap of top 50 up- and downregulated genes; ( D ) Enriched Hallmark and Reactome gene sets identified by GSEA (FDR < 25%, nominal p < 0.05)

    Techniques Used: Microarray

    Apoptosis-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched apoptosis-related gene sets (GSEA); ( B ) Annexin V/PI apoptosis quantification at IC₅₀ and 5 µg/mL; (C) RT-qPCR validation of selected apoptosis-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)
    Figure Legend Snippet: Apoptosis-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched apoptosis-related gene sets (GSEA); ( B ) Annexin V/PI apoptosis quantification at IC₅₀ and 5 µg/mL; (C) RT-qPCR validation of selected apoptosis-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Techniques Used: Quantitative RT-PCR, Biomarker Discovery

    Proliferation-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) AlamarBlue proliferation kinetics at IC₅₀ and 5 µg/mL; ( B ) Cell cycle phase distribution by flow cytometry; ( C ) RT-qPCR validation of selected proliferation-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)
    Figure Legend Snippet: Proliferation-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) AlamarBlue proliferation kinetics at IC₅₀ and 5 µg/mL; ( B ) Cell cycle phase distribution by flow cytometry; ( C ) RT-qPCR validation of selected proliferation-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Techniques Used: Flow Cytometry, Quantitative RT-PCR, Biomarker Discovery

    Cell motility-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched motility-related Reactome gene sets (GSEA); ( B ) Spatial characteristics of the microfluidic device; ( C ) Confined 3D migration parameters (speed, velocity, migratory cell number) at IC₅₀ and 5 µg/mL. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)
    Figure Legend Snippet: Cell motility-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched motility-related Reactome gene sets (GSEA); ( B ) Spatial characteristics of the microfluidic device; ( C ) Confined 3D migration parameters (speed, velocity, migratory cell number) at IC₅₀ and 5 µg/mL. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Techniques Used: Migration



    Similar Products

    dld1 ecacc  (ATCC)
    99
    ATCC dld1 ecacc
    In vitro antitumor activity of undigested and digested red grape anthocyanin extracts in <t>DLD1</t> and Caco2 cells. ( A ) MTT cell viability curves; ( B ) IC₅₀ values and relative potency; ( C ) Representative cell morphology of untreated (CTR) and IC₅₀-treated cells; ( D ) Trypan Blue viability validation in DLD1 cells. Statistical significance was assessed by t-test and Extra Sum-of-Squares F Test
    Dld1 Ecacc, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dld1 ecacc/product/ATCC
    Average 99 stars, based on 1 article reviews
    dld1 ecacc - by Bioz Stars, 2026-06
    99/100 stars
    		  Buy from Supplier

    Image Search Results


    In vitro antitumor activity of undigested and digested red grape anthocyanin extracts in DLD1 and Caco2 cells. ( A ) MTT cell viability curves; ( B ) IC₅₀ values and relative potency; ( C ) Representative cell morphology of untreated (CTR) and IC₅₀-treated cells; ( D ) Trypan Blue viability validation in DLD1 cells. Statistical significance was assessed by t-test and Extra Sum-of-Squares F Test

    Journal: Plant Foods for Human Nutrition (Dordrecht, Netherlands)

    Article Title: Gastrointestinal Digestion Enhances the In vitro Antitumor Activity of Red Grape Anthocyanins Against Colorectal Cancer Cells

    doi: 10.1007/s11130-026-01498-w

    Figure Lengend Snippet: In vitro antitumor activity of undigested and digested red grape anthocyanin extracts in DLD1 and Caco2 cells. ( A ) MTT cell viability curves; ( B ) IC₅₀ values and relative potency; ( C ) Representative cell morphology of untreated (CTR) and IC₅₀-treated cells; ( D ) Trypan Blue viability validation in DLD1 cells. Statistical significance was assessed by t-test and Extra Sum-of-Squares F Test

    Article Snippet: Two human colorectal carcinoma cell lines, Caco2 (ATCC, USA) and DLD1 (ECACC), were cultured under standard conditions as detailed in SM.

    Techniques: In Vitro, Activity Assay, Biomarker Discovery

    Transcriptomic alterations in DLD1 cells treated with IC₅₀ of digested red grape anthocyanins. ( A ) Hierarchical clustering of microarray samples; ( B ) Volcano plot of differentially expressed genes (|FR| ≥ 1.5; adj. p < 0.05); ( C ) Heatmap of top 50 up- and downregulated genes; ( D ) Enriched Hallmark and Reactome gene sets identified by GSEA (FDR < 25%, nominal p < 0.05)

    Journal: Plant Foods for Human Nutrition (Dordrecht, Netherlands)

    Article Title: Gastrointestinal Digestion Enhances the In vitro Antitumor Activity of Red Grape Anthocyanins Against Colorectal Cancer Cells

    doi: 10.1007/s11130-026-01498-w

    Figure Lengend Snippet: Transcriptomic alterations in DLD1 cells treated with IC₅₀ of digested red grape anthocyanins. ( A ) Hierarchical clustering of microarray samples; ( B ) Volcano plot of differentially expressed genes (|FR| ≥ 1.5; adj. p < 0.05); ( C ) Heatmap of top 50 up- and downregulated genes; ( D ) Enriched Hallmark and Reactome gene sets identified by GSEA (FDR < 25%, nominal p < 0.05)

    Article Snippet: Two human colorectal carcinoma cell lines, Caco2 (ATCC, USA) and DLD1 (ECACC), were cultured under standard conditions as detailed in SM.

    Techniques: Microarray

    Apoptosis-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched apoptosis-related gene sets (GSEA); ( B ) Annexin V/PI apoptosis quantification at IC₅₀ and 5 µg/mL; (C) RT-qPCR validation of selected apoptosis-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Journal: Plant Foods for Human Nutrition (Dordrecht, Netherlands)

    Article Title: Gastrointestinal Digestion Enhances the In vitro Antitumor Activity of Red Grape Anthocyanins Against Colorectal Cancer Cells

    doi: 10.1007/s11130-026-01498-w

    Figure Lengend Snippet: Apoptosis-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched apoptosis-related gene sets (GSEA); ( B ) Annexin V/PI apoptosis quantification at IC₅₀ and 5 µg/mL; (C) RT-qPCR validation of selected apoptosis-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Article Snippet: Two human colorectal carcinoma cell lines, Caco2 (ATCC, USA) and DLD1 (ECACC), were cultured under standard conditions as detailed in SM.

    Techniques: Quantitative RT-PCR, Biomarker Discovery

    Proliferation-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) AlamarBlue proliferation kinetics at IC₅₀ and 5 µg/mL; ( B ) Cell cycle phase distribution by flow cytometry; ( C ) RT-qPCR validation of selected proliferation-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Journal: Plant Foods for Human Nutrition (Dordrecht, Netherlands)

    Article Title: Gastrointestinal Digestion Enhances the In vitro Antitumor Activity of Red Grape Anthocyanins Against Colorectal Cancer Cells

    doi: 10.1007/s11130-026-01498-w

    Figure Lengend Snippet: Proliferation-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) AlamarBlue proliferation kinetics at IC₅₀ and 5 µg/mL; ( B ) Cell cycle phase distribution by flow cytometry; ( C ) RT-qPCR validation of selected proliferation-associated genes. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Article Snippet: Two human colorectal carcinoma cell lines, Caco2 (ATCC, USA) and DLD1 (ECACC), were cultured under standard conditions as detailed in SM.

    Techniques: Flow Cytometry, Quantitative RT-PCR, Biomarker Discovery

    Cell motility-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched motility-related Reactome gene sets (GSEA); ( B ) Spatial characteristics of the microfluidic device; ( C ) Confined 3D migration parameters (speed, velocity, migratory cell number) at IC₅₀ and 5 µg/mL. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Journal: Plant Foods for Human Nutrition (Dordrecht, Netherlands)

    Article Title: Gastrointestinal Digestion Enhances the In vitro Antitumor Activity of Red Grape Anthocyanins Against Colorectal Cancer Cells

    doi: 10.1007/s11130-026-01498-w

    Figure Lengend Snippet: Cell motility-related effects of digested red grape anthocyanins in DLD1 cells. ( A ) Enriched motility-related Reactome gene sets (GSEA); ( B ) Spatial characteristics of the microfluidic device; ( C ) Confined 3D migration parameters (speed, velocity, migratory cell number) at IC₅₀ and 5 µg/mL. * p < 0.05, ** p < 0.01, *** p < 0.001 (t-test)

    Article Snippet: Two human colorectal carcinoma cell lines, Caco2 (ATCC, USA) and DLD1 (ECACC), were cultured under standard conditions as detailed in SM.

    Techniques: Migration